Oligonucleotide Therapeutics
Discover your future in Oligonucleotide therapeutics
Our customized services
- Design and synthesis of novel nucleosides for the synthesis of engineered oligonucleotides and synthetic RNA´s
- Stability study and capability of handling the synthesis and purification of relatively unstable nucleotide triphosphate monomer
- Isolation, characterization and providing the synthesis support of starting material (monomer, nucleoside) related impurity present in Oligonucleotide API
- Analytical standard for the stable metabolites - nucleoside, monomer and nucleotide (up to dinucleotides)
- Process development and large-scale synthesis support of key building blocks; modified sugar, base, nucleoside & (d) NTPs (gram to Kg scale).
Our Expertise
Synthesis and modification of (d)NTPs- (2`-deoxy)ribonucleoside triphosphate
Synthesis of customized nucleosides, nucleotides, dinucleotides, phosphoroamidates, thiophosphates, triphosphates, & monophosphates e.g.: Labelled.
Synthesis support on various phosphorodiamidate morpholinos (PMOs)
Design & synthesis of sugar building block for various locked Nucleic acid (LNA), bridge Nucleic acid (BNAs ), bicyclo-DNA (bc-DNA ), & tricylo DNA (tc-DNA).
Looking for Focused & Solution-oriented chemistry services?
Synthetic Organic Chemistry
Custom Synthesis
As a leading Contract Research Organization in Europe, Taros provides valuable contract discovery for synthetic organic chemistry, chemical process development, and…
Process optimization and scale-up
Process Development
Making advantage of their expertise in organic chemistry and taking a design of experiments (DoE) approach to process development, our scientific teams in Germany…
Looks interesting?
As a leading CRO in Europe, Taros provides comprehensive drug discovery chemistry services for large Pharma and Biotech corporations as well as for Research Institutes and Academia
Our experienced chemists practice a pragmatic culture and customer-centric approach in order to exceed project expectations and, despite challenges, bridge very narrow timelines. They are trained to consider economic, safety and ecological boundaries and conditions laid out for all stages of the project.
